Research
Our technology is rooted in over a decade of academic sleep research. Discover the extensive list of publications in renowned scientific journals and ongoing research projects.
35 papers published
6 studies ongoing
Published
Predicting and phase targeting brain oscillations in real-time
A systematic assessment of M-CLNS Mark II (DeepSleep technology) performance, across different sleep-wake states (non-REM sleep, REM sleep, wake), target frequencies (delta, theta, alpha)
and phases, showing high performance of the method in all applications.
Biorxiv
S. Jongejan, Lucia M. Talamini, A.C. vd Heijden
October 12, 2024
Original paper
Original paper
Published
Sleep-Based Memory Reactivation Boosts PTSD Treatment Outcome
First clinical project. In this study, our technology M-CLNS Mark II was applied in patients with post-traumatic stress disorder (PTSD), to reactivate and consolidate successful therapy memories during sleep and enhance therapy effectiveness. The study shows application of M-CLNS in this population with severely disturbed sleep is feasible, safe and shows promising therapeutic effects.
Current Biology
Corresponding author Hein J.F. van Marle
August 19, 2024
Original paper
Original paper
Ongoing
Sleep Deep: Registration clinical scientific research: home sleep improvement in patients (PTSD) using DeepSleep
Registration of a for clinical scientific research in the Netherland: study assessing at-home sleep improvement in patients with post-traumatic stress disorder (PTSD), using M-CLNS Mark II.
Amsterdam University Medical Center
Lucia Talamini
October 1, 2023
Original paper
Original paper
More research
We are constantly pursuing innovation through more and new research. In the Memory & Sleeping Lab in Amsterdam, in our ongoing at home trails but also together with partners that utilize our technology to measure impact on related (health) issues.
Ongoing
Long-term at home sleep improvement in insomnia with M-CLNS Mark II
Czech Technical University in Prague
Marek Piorecky
Jun 1, 2023
Original paper
Original paper
Published
Sleep as a window to target traumatic memories
Neuroscience & Biobehavioral Reviews
v Marle,Lucia M. Talamini et AL.
Mar 10, 2023
Original paper
Original paper
Ongoing
Boosting sleep slow waves suppresses dreaming
Biorxiv preprint
Lucia M. Talmini et Al.
Mar 10, 2023
Original paper
Original paper
Published
Sound Asleep: Processing and Retention of Slow Oscillation Phase-Targeted Stimuli
Neuroscience & Biobehavioral Reviews
Corresponding author Martin Dresler
Feb 20, 2023
Original paper
Original paper
Published
Stabilizing Sleep Through Closed-Loop Acoustic Stimulation: Implications for Obstructive Sleep Apnea Treatment
Springer International Journal
Lucia M. Talamini
Jan 8, 2022
Original paper
Original paper
Published
The looping lullaby: Closed-Loop Neurostimulation decreases sleepers sensitivity to environmental noise
biorxiv
Lucia Talamini 4,6,9
Aug 8, 2021
Original paper
Original paper
Published
Sleep as a window to treat affective disorders
Current Opinion in Behavioral Sciences
Lucia M. Talamini
Mar 6, 2020
Original paper
Original paper
Published
Manipulating memory during sleep
Sleep Medicine
Lucia T. Talamini, E. van Poppel
Dec 16, 2019
Original paper
Original paper
Published
Slow Oscillations during Sleep Coordinate Interregional Communication in Cortical Networks
Journal of Neuroscience
Lucia M. Talamini, oy Cox Et Al.
Dec 10, 2014
Original paper
Original paper
Published
Sound Asleep: Processing and Retention of Slow Oscillation Phase-Targeted Stimuli
National Library of Medicine
Lucia. M. Talamini et al.
Jul 7, 2014
Original paper
Original paper